Medicine

Latest articles

1. 1. Medicine

   An Unexpected Role of Neutrophils in Clearing Apoptotic Hepatocytes In Vivo

   Luyang Cao, Lixiang Ma ... Jingsong Xu
2. 1. Developmental Biology
   2. Medicine

   Vertical transmission of maternal mitochondrial DNA through extracellular vesicles modulates embryo bioenergetics

   David Bolumar, Javier Moncayo-Arlandi ... Felipe Vilella
3. 1. Medicine

   Epidemiological characteristics and prevalence rates of research reproducibility across disciplines: a scoping review of articles published in 2018-2019

   Kelly D Cobey, Christophe A Fehlmann ... David Moher
4. 1. Medicine

   Development and biophysical characterization of a humanized FSH-blocking monoclonal antibody therapeutic formulated at an ultra-high concentration

   Satish Rojekar, Anusha R Pallapati ... Mone Zaidi
5. 1. Medicine

   The generation of HepG2 transmitochondrial cybrids to reveal the role of mitochondrial genotype in idiosyncratic drug-induced liver injury

   Amy Louise Ball, Carol E Jolly ... Amy E Chadwick

   HepG2 transmitochondrial cybrids of haplogroup J genome had increased sensitivity to aspects of mitochondrial dysfunction induced by tolcapone and 2-hydroxyflutamide, compared to haplogroup H, thus cybrids provide a practical system to investigate the consequences of mitochondrial genome on drug-induced hepatotoxicity.
6. 1. Cell Biology
   2. Medicine

   Reciprocal interactions between alveolar progenitor dysfunction and aging promote lung fibrosis

   jiurong Liang, Guanling Huang ... Dianhua Jiang
7. 1. Immunology and Inflammation
   2. Medicine

   Anti-inflammatory therapy with nebulised dornase alfa in patients with severe COVID-19 pneumonia A Randomised Clinical Trial

   Joanna C. Porter, Jamie Inshaw ... Venizelos Papayannopoulos
8. 1. Cell Biology
   2. Medicine

   ErbB signaling is a potential therapeutic target for vascular lesions with fibrous component

   Suvi Jauhiainen, Henna Ilmonen ... Johanna P Laakkonen

   Experimentation on patient biopsies, cell culture, and xenograft models demonstrates involvement of ErbB signaling and fibroblasts in lesion growth, implying that targeting of both stromal and endothelial cells could be a beneficial treatment strategy for patients with venous lesions.
9. 1. Medicine

   Loss of PTPMT1 limits mitochondrial utilization of carbohydrates and leads to muscle atrophy and heart failure

   Hong Zheng, Qianjin Li ... Cheng-Kui Qu
10. 1. Immunology and Inflammation
    2. Medicine

    β-carotene accelerates resolution of atherosclerosis by promoting regulatory T cell expansion in the atherosclerotic lesion

    Ivan Pinos, Johana Coronel ... Jaume Amengual