Microbiology and Infectious Disease

Microbiology and Infectious Disease

eLife reviews research covering virology, bacteriology and mycology. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Developmental Biology
    2. Microbiology and Infectious Disease

    Intestinal GCN2 controls Drosophila systemic growth in response to Lactiplantibacillus plantarum symbiotic cues encoded by r/tRNA operons

    Théodore Grenier, Jessika Consuegra ... François Leulier
    Bacterial ribosomal and transfer RNAs are symbiotic clues sensed by host general control nonderepressible 2 to support Drosophila systemic growth.
    1. Microbiology and Infectious Disease

    Role of cytoneme structures and extracellular vesicles in Trichomonas vaginalis parasite-parasite communication

    Nehuén Salas, Manuela Blasco Pedreros ... Natalia de Miguel
    Understanding communication mechanisms between unicellular parasites is crucial in the development of novel therapies, as they rely on diverse modes of communication (like extracellular vesicle release, cytoneme, and filopodia formation) to regulate their behavior and survival.
    1. Microbiology and Infectious Disease

    Parasite Communication: Learning the language of pathogens

    Izadora Volpato Rossi, Marcel Ivan Ramirez
    Parasites can use extracellular vesicles and cellular projections called cytonemes to communicate with one another.
    Formats available:
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    1. Microbiology and Infectious Disease
    2. Neuroscience

    Bacterial meningitis in the early postnatal mouse studied at single-cell resolution

    Jie Wang, Amir Rattner, Jeremy Nathans
    A model of early postnatal bacterial meningitis in the mouse demonstrates the transcriptome responses of each of the major meningeal cell types and should prove useful in dissecting the pathophysiology of bacterial meningitis in human infants.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Regulation of inflammation and protection against invasive pneumococcal infection by the long pentraxin PTX3

    Rémi Porte, Rita Silva-Gomes ... Alberto Mantovani
    Long Pentaxin 3 is highly expressed by non-hematopoietic cells during Streptococcus pneumoniae invasive infections and regulates polymorphonuclear neutrophils' recruitment through interaction with P-selectin which damps inflammation-associated tissue damage and pneumococcal systemic dissemination.
    1. Microbiology and Infectious Disease

    Phage tRNAs evade tRNA-targeting host defenses through anticodon loop mutations

    Daan F van den Berg, Baltus A van der Steen ... Stan JJ Brouns
    A new perspective on the 50-year old mystery of why phages encode their own tRNAs.
    Short Report Updated
    Formats available:
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Senior editors

  1. Arturo Casadevall
    Johns Hopkins Bloomberg School of Public Health, United States
  2. Wendy S Garrett
    Wendy S Garrett
    Harvard T.H. Chan School of Public Health, United States
  3. Päivi Ojala
    University of Helsinki, Finland
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