Physics of Living Systems

Physics of Living Systems

eLife reviews research in which approaches from the physical sciences are used to provide insights into the properties of biological systems and processes. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology
    2. Physics of Living Systems

    Physical basis of the cell size scaling laws

    Romain Rollin, Jean-François Joanny, Pierre Sens
    A theoretical model explains how protein density and nuclear to cell volume ratio are maintained during cell growth, discusses conditions under which this breaks down, and highlights the importance of metabolites, mainly amino acids such as glutamate, in this homeostasis.
    1. Cell Biology
    2. Physics of Living Systems

    Cell Size: Putting scaling laws on a physical foundation

    Yiyang Ye, Jie Lin
    As a cell changes size during the cell cycle, why does its density remain constant?
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    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Substrate stiffness impacts early biofilm formation by modulating Pseudomonas aeruginosa twitching motility

    Sofia Gomez, Lionel Bureau ... Sigolene Lecuyer
    The spatial organization of pathogenic bacteria into microcolonies can be shaped by the stiffness of the substrate that they colonize, via modifications of the bacterial motility.
    1. Physics of Living Systems

    Vein fate determined by flow-based but time-delayed integration of network architecture

    Sophie Marbach, Noah Ziethen ... Karen Alim
    Relative hydraulic resistance, shear rate, and pressure in a vascular network integrate the network's architecture via fluid flow, and determine vein dynamics, with a time delay, in the prototypical organism Physarum polycephalum.
    1. Physics of Living Systems

    Vasculature: Exploring the dynamics of vascular adaptation

    Thomas S Shimizu, E Toby Kiers, Howard A Stone
    A combination of in toto imaging and theory suggests a new mechanism for the remodeling of veins in vascular networks.
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    1. Medicine
    2. Physics of Living Systems

    Comparable in vivo joint kinematics between self-reported stable and unstable knees after TKA can be explained by muscular adaptation strategies: A retrospective observational study

    Longfeng Rao, Nils Horn ... Pascal Schütz
    Muscle synergies are able to identify muscular adaptation that results from feelings of joint instability, whereas tibiofemoral kinematics are sensitive for detecting acute instability events during functional activities.

Senior editors

  1. Aleksandra Walczak
    Ecole Normale Superieure, France
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